赵建宁，南京军区南京总医院骨科主任，主任医师，教授，南京大学、第二军医大学、南京医科大学和南方医科大学博士生导师，博士后联系导师，技术三级，文职一级，享受国务院政府特殊津贴和军队优秀人才特殊津贴。江苏省有突出贡献中青年专家，荣立三等功2次。 全军骨科专业委员会副主任委员、关节外科主任委员，全国关节外科委员，髋关节外科工作委员会执委，副组长, 膝关节外科工作委员会委员，全国和全军残疾人学会肢体残疾委员会副主任委员，中国医师协会骨科专业委员，关节外科常务委员，全军运动医学及关节镜学会委员，中国老年学会脊柱关节疾病专业委员会常务委员，华裔骨科学会理事，亚太人工关节学会中国分会理事。江苏省和南京市骨科专业副主任委员，江苏省中西医结合学会骨伤专业副主任委员，南京军区显微外科专业主任委员，南京军区骨科专业副主任委员等。并担任《医学研究生学报》副主编、《中华创伤骨科杂志》、《中国骨与关节损伤杂志》、《中国矫形外科杂志》、《中国骨伤》、《中华解剖与临床》、《The Jourmai of Arthroplasty》中文版杂志等杂志的常务编委和编委。 主要研究方向为人工关节置换术后无菌性松动的防治和关节软骨损伤的早期诊断和修复。获国家自然科学基金等课题9项，省部级科技进步奖14项，其中二等奖6项，获国家专利6项，主译或参与编写专著6部，以第一和通讯作者发表论文300余篇，其中SCI论文42篇，总影响因子104.527，最高影响因子11.753。至今已培养25名博士生，已毕业15名，54名硕士生毕业。 2016年拟招收1-2名博士后，要求博士年龄30岁以下。 近5年科研情况汇总 SCI文章 序号 论文题目 杂志名称 作者 发表 年月 卷 期 页码 1 Autophagy mediated CoCrMo particle-induced peri-implant osteolysis by promoting osteoblast apoptosis Autophagy IF 11.753 赵建宁 2015 11 12 2358 - 2369 2 Polymorphisms in TP53 are associated with risk and survival of osteosarcoma in a Chinese population International Journal of Clinical and Experimaental Pathology IF 1.891 赵建宁 2015 8 3 3198-3203 3 The fibroblast expression of RANKL in CoCrMO-Particle-induced osteolysis is mediated by ER stress and XBP1s Acta biomaterialia IF 6.025 赵建宁 2015 24 352-360 4 ER stress mediated TiAl6V4 particle-induced peri-implant osteolysis by promoting RANKL expression in fibroblasts Plos One IF 3.234 赵建宁 2015 10 9 e0137774 5 Expression of XBP1s in Fibroblasts is Critical for TiAl6V4 Particle-Induced RANKL Expression and Osteolysis Journal of Orthopaedic Research IF 2.986 赵建宁 2015 ONLINE 6 Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism Int J Clin Exp Pathol IF 1.891 赵建宁 2015 8 5 5044-5052 7 The flavonoid ampelopsin inhibited cell growth and induced apoptosis and G0/G1 arrest in human osteosarcoma MG-63 cells in vitro Pharmazie IF 1.052 赵建宁 2015 70 6 388-393 8 Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaking pathway Molecular medicine reports IF 1.554 赵建宁 2015 12 1 1499-1505 9 Inhibition of Microtubule Dynamics Affects Podosome Belt Formation During Osteoclast Induction Cell Biochemistry and Biophysics IF 1.68 赵建宁 2015 71 2 741-747 10 Expression and clinical significance of cyclooxygenase-2 and microRNA-143 in osteosarcoma Experimental and therapeutic medicine IF 1.269 赵建宁 2015 9 6 2374-2378 11 A single nucleotide polymorphism in the TGF-B1 gene(rs1982073C>T)may contribute to increased risks of bone fracture,osteoporosis,and osteoarthritis:a meta-analysis Clin rheumatol IF 1.696 赵建宁 2014 36 3 2059-2064 12 Exchanging reamed nailing versus augmentative compression plating with autogenous bone grafting for aseptic femoral shaft nonunion: A retrospective cohort study Editorial Manager IF 0.614 赵建宁 2015 49 6 668-675 13 Osteoprotective effect of combination therapy of low-dose oestradiol with G15, a specific antagonist of GPR30/GPER in ovariectomy-induced osteoporotic rats Bioscience Reports IF 2.637 赵建宁 2015 35 4 94-100 14 Endoplasmic reticulum stress-mediated inflammatory signaling pathways within the osteolytic periosteum and interface membrane in particle-induced osteolysis Cell and Tissue Research IF 3.565 赵建宁 2015 15 Anxiolytic-like effects of translocator protein (TSPO) ligand ZBD-2 in an animal model of chronic pain Molecular pain IF 3.654 赵建宁 2015 16 Osteoprotective effects of estrogen membrane receptor GPR30 in ovariectomized rats The journal of steroid Biochemistry and Molecular Bioiogy IF 3.628 赵建宁 2015 154 237-244 17 Associations of poiymorphisma in the bone morphogenetic protein-2 gene with risk and prognosis of osteosarcoma in a Chinese population Tumor Bio IF 3.611l 赵建宁 2015 36 3 2059-2064 18 Comparing Accuracy of Cervical Pedicle Screw placement between a Guidance System and Manual Manipulation:A Cadaver study Med Sci Monit IF 1.433 赵建宁 2015 21 2672-2677 19 Sox4 enhances chondrogenic differentiation and proliferation of human synovium-derived stem cell via activation of long noncoding RNA DANCR Journal of Molecular Histology IF 1.815 赵建宁 2015 46 6 467-473 20 Tumor-Suppressing Effects of miR-141 in Human Osteosarcoma Cell Biochemistry and Biophysics IF2.38 赵建宁 2014 69 319-325 21 Tumor- Suppressing Effects of miR-451 in Human Osteosarcoma Cell Biochemistry and Biophysics IF2.38 赵建宁 2014 70 215-224 22 Down-Regulation of miR-3928 Promoted Osteosarcoma Growth Cell Biochemistry and Biophysics IF2.38 赵建宁 2014 69 163-168 23 Learning Curve of Full-Endoscopic Technique Through Interlaminar Approach for L5/S1 DISK herniations Cell Biochemistry and Biophysics IF2.38 赵建宁 2014 33 1547-1556 24 Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation Patients Cell Biochemistry and Biophysics IF2.38 赵建宁 2014 18 1069-1072 25 Quantitative Assessment of the Association Between HDMX Polymorphism and Sarcoma Cell Biochemistry and Biophysics IF2.38 赵建宁 2014 15 8577-8579 26 Correlation of Matrix Metalloproteinases-1 and Tissue Inhibitor of Metalloproteinases-1 with Patient Age and Grade of Lumbar Disk Herniation Cell Biochemistry and Biophysics IF2.38 赵建宁 2014 70 1219-1225 27 Research Progress on the Livin Gene and Osteosarcomas Asian Pacific Journal of Cancer Prevention IF1.5 赵建宁 2014 70 1671-1676 28 Tumor- Suppressing Effects of miR-429 on Human Osteosarcoma Cell Biochemistry and Biophysics IF2.38 赵建宁 2014 69 439-444 29 Down-Regulation of Adiponectin Receptors in Osteoarthritic Chondrocytes Cell Biochem Biophys IF2.38 赵建宁 2014 70 491-497 30 MiR-143 inhibits EGFR-signaling-dependent osteosarcoma invasion Tumor Biol IF2.84 赵建宁 2014 35 12743-12748 31 Particle-induced osteolysis mediated by endoplasmic reticulum stress in prosthesis loosening BIOMATERIALS IF 8.312 赵建宁 2013 34 11 2611-2623 32 Reply to comment on Bao et al.: Lesser trochanteric osteotomy in total hip arthroplasty for treating CROWE type IV developmental dysplasia of hip INTERNATIONAL ORTHOPAEDICS IF 2.319 赵建宁 2013 37 5 987-987 33 Lesser trochanteric osteotomy in total hip arthroplasty for treating CROWE type IV developmental dysplasia of hip INTERNATIONAL ORTHOPAEDICS IF2.319 赵建宁 2013 37 3 385-390 34 Free fatty acids are responsible for the hidden blood loss in total hip and knee arthroplasty Medical Hypotheses IF 1.054 赵建宁 2013 3 104-107 35 Significant pathways detection in Osteoporosis based on the bibliometric network EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES IF1.093 赵建宁 2013 17 1 1-7 36 MicroRNAs in osteosarcoma: From biological players to clinical contributors, a review JOURNAL OF INTERNATIONAL MEDICAL RESEARCH IF0.958 赵建宁 2013 41 1 1-12 37 Design and preliminary biomechanical analysis of artificial cervical joint complex Archivesof orthopaedlc and traumasurgery IF1.358 赵建宁 2013 133 6 735-743 38 The canonical Wnt-beta-catenin pathway in development and chemotherapy of osteosarcoma Frontiers in Bioscience IF3.286 赵建宁 2013 6 1 1384-1391 39 CaMKII activates ASK1 to induce apoptosis of spinal astrocytes under oxygen-glucose deprivation Cellular and molecular neuroblology IF 0.98 赵建宁 2013 33 4 543-549 40 Systematic screen with kinases inhibitors reveala kinases play distinct roles in growth of osteoprogenitor cells Int J Clin Exp pathol IF 2.242 赵建宁 2013 6 10 2082-2091 41 Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffolds Biomaterials IF8.312 赵建宁 2011 3 4 科研课题 序号 项目名称 项目来源 经费（万） 完成人 起止时间 1 磨损微粒诱导的成骨细胞自噬在关节假体周围无菌性松动发病中的作用及机制研究81572111 国家自然科学基金 57 赵建宁 2016.1-2019.12 2 内质网应激抑制剂4-Phenylbutyrate（4-PBA）减轻磨损微粒诱导骨溶解的机制研究 南京市科研课题 5 赵建宁 2014.1-2017.1 3 江苏省骨科临床研究中心 江苏省科技厅 150 赵建宁 2012.5-2015.12 4 抗假体松动骨水泥的研制及其抑制关节置换后骨溶解中的作用 江苏省自然基金 10 赵建宁 2012.7-2015.6 5 抗假体松动骨水泥的研制及其抑制关节置换后骨溶解的机制研究 军区重点课题 20 赵建宁 2012.1-2014.12